Occupational exposure to beryllium and cancer risk: A …
Exposure to fluorides and copper was highly correlated to beryllium exposure, and the results on lung cancer risk paralleled those for beryllium. An indirect adjustment for smoking was performed using the data from a survey of about 10% of workers who were employed in 1968 (this appears to be the same survey used to adjust …
Beryllium Toxicity: Who Is at Risk of Exposure to …
Anyone working with or around beryllium metal, ceramics, alloys, or salts is at risk of developing beryllium sensitization or disease from inhaling small particles. Very low …
Biomonitoring Summary | CDC
The effects of occupational exposure to beryllium depend on the concentration of beryllium in the inhaled air and the duration of air exposure. Air levels greater than 100 µg/m3 can result in erythema and edema of the lung mucosa, which produces pneumonitis. ... Maier L. Genetic and exposure risks for chronic beryllium disease. Clin ChestMed ...
CCOHS: Beryllium
Exposure to beryllium can lead to sensitization - an allergic-type response. Not all workers will develop sensitivity to beryllium. In most cases, a worker may be sensitized but there are no health symptoms. A blood test called beryllium lymphocyte proliferation test (BeLPT) can measure how blood cells react to beryllium. This test can …
About Beryllium | Department of Energy
Exposure to beryllium particles can cause a serious illness in certain people. This illness is chronic beryllium disease, or CBD-an irreversible and sometimes fatal scarring of the lungs. Medical studies show that even small amounts of beryllium particles of a size that can be breathed deeply into the lungs may trigger an allergy-like ...
Managing Health Effects of Beryllium Exposure
Managing Health Effects of Beryllium Exposure - NCBI Bookshelf. Beryllium is a lightweight metal that is used for its exceptional strength and high heat-absorbing capability. Beryllium and its alloys can be found in many important technologies in the defense and aeronautics industries, such as nuclear devices, satellite systems, radar systems ...
Summary
Thus, the committee considered risks posed by beryllium exposure broadly to include all forms of beryllium. The immunopathogenic mechanisms underlying BeS and progression to CBD have been …
Summary | Health Effects of Beryllium Exposure: A …
The first is to provide a review of the scientific literature on beryllium, and the second will expand more critically on the review in considering the maximum chronic inhalation exposure levels that are unlikely to produce adverse health effects, in estimating carcinogenic risks, and in providing guidance on testing methods for surveillance ...
What Are the U.S. Standards for Beryllium Exposure?
Table 1 shows standards and regulations for beryllium. The occupational exposure limit of 2.0 micrograms per cubic meter (µg/m 3) of air for an 8-hour work shift for beryllium has been used in the workplace since the late 1940s.However, recent research has shown that the 2.0 mg/m 3 standard is not protective (For example, see the ACGIH standards). ). …
Beryllium and you
This leaflet is for people who work with beryllium and its compounds. It tells you about the possible health effects – short-term and long-term – and explains what you and your employer should do to control the risks. This leaflet tells employees about the possible health hazards of beryllium and its compounds, the preventative measures ...
Beryllium, Cadmium, Mercury, and Exposures in the Glass …
This volume evaluates the carcinogenic risk to humans posed by exposure to selected metals and their compounds. Separate monographs are presented for beryllium and beryllium compounds, cadmium and cadmium compounds, and mercury and inorganic and methylmercury compounds. Because several metallic salts and pigments are used in the …
Berylliosis (Chronic Beryllium Disease): Symptoms
While higher-level exposures can increase the risk of developing the disease, even people with very limited exposure to beryllium can become sensitized to beryllium and develop CBD. If you work in a job where you have known beryllium exposure, your employer should offer regular screenings for beryllium sensitization and …
Beryllium Compounds
Chronic (long-term) inhalation exposure of humans to beryllium has been reported to cause chronic beryllium disease (berylliosis), in which granulomatous lesions (noncancerous) develop in the lung. Human epidemiology studies are limited, but suggest a causal relationship between beryllium exposure and an increased risk of lung cancer.
Exposure Assessment
The committee has reviewed the literature describing exposure to beryllium to provide a basis for examining questions relevant to the identification of exposure-response relationships and the development of health-protection standards. Worker-protection standards are the focus of this effort, but an understanding of natural background …
Frequently Asked Questions: Beryllium and Beryllium …
Identify adverse health effects associated with beryllium exposure so that appropriate actions can be taken, including re-evaluating engineering controls or providing medical removal protection benefits. Determine if an employee has been sensitized to beryllium and at risk of developing CBD. Determine the employee's fitness to use respirators.
Managing Health Effects of Beryllium Exposure.
It is well established that beryllium causes sensitization (beryllium sensitization, BeS) and chronic beryllium disease (CBD). This chapter assesses the risk of those conditions posed by occupational exposure …
Health Effects of Beryllium Exposure: A Literature Review
As described by Kreiss et al. (2007), its diverse uses may put a growing number of workers at risk of beryllium exposure. Henneberger et al. (2004) relied on sampling compliance data from the Occupational Safety and Health Administration (OSHA) to estimate that 134,000 U.S. workers are potentially exposed to beryllium; however, Kreiss et al ...
Health Effects of Beryllium Exposure: A Literature Review
Chapter 2 reviews exposure factors important for assessing health risks associated with beryllium. It includes a review of the exposure assumptions that underlie existing exposure standards, consideration of exposures in natural and anthropogenic settings, and an examination of how physiochemical characteristics and particle sizes are ...
Beryllium Toxicity: Patient Education Care Instruction …
Exposure to beryllium can affect the lungs and/or skin. However, not everyone will develop health effects from beryllium exposure. People who work closely with beryllium as part of …
Beryllium exposure: dermal and immunological considerations …
Objective: People exposed to beryllium compounds are at increased risk of developing beryllium sensitization and chronic beryllium disease (CBD). The purpose of this short communication is to present information regarding the potential importance of skin exposure to beryllium, an exposure and alternate immune response pathway to the …
Biological Exposure Metrics of Beryllium-Exposed Dental …
Lower levels of exposure, however, were reported as posing a risk of sensitization in individuals directly and indirectly exposed to beryllium. 1 Although there have been efforts to protect Be-exposed workers, the current occupational health standards for Be do not provide adequate protection against the development of CBD or sensitization. 2
Beryllium Toxicity
Beryllium exposure and toxicity can cause serious acute and long-term health effects, making its immediate identification and …
Managing Health Effects of Beryllium Exposure.
To help determine the steps necessary to protect its workforce from the adverse effects of exposure to beryllium used in military aerospace applications, the U.S. Air Force requested that the National Research …
ToxGuide for Beryllium
risk for beryllium exposure. Workers' family members may also be exposed to beryllium from contaminated clothing. Toxicokinetics and Biomonitoring Toxicokinetics Inhalation is the primary route of beryllium absorption in humans, but data on the rate and extent of absorption of inhaled beryllium in humans are limited.
Medical Surveillance for Beryllium‑Exposed Workers
the employee at increased risk from further airborne exposure, or any medical conditions related to airborne exposure that require further evaluation or treatment), • Any recommendations on the employee's use of PPE or respirators, • Any limitations on the employee's airborne beryllium exposure, and • Any recommendation for referral to a
Beryllium
Who is at risk from exposure to beryllium? What is Chronic Beryllium Disease (CBD)? What is beryllium sensitization? How will the beryllium rule protect workers' health? Need …
Federal Register :: Occupational Exposure to Beryllium
In developing its review of the preliminary health effects from beryllium exposure and assessment of risk for the NPRM, OSHA prepared a Start Printed Page 2481 pair of draft documents, entitled "Occupation Exposure to Beryllium: Preliminary Health Effects Evaluation" (OSHA, 2010, Document ID 1271) and "Preliminary Beryllium …
Beryllium
An increased risk of lung cancer has been observed in workers exposed to beryllium or beryllium compounds. How can exposure be reduced? The U.S. Occupational Safety & Health …
Genetic and exposure risks for chronic beryllium disease
Occasional, direct exposure to beryllium through machining and grinding of copper–beryllium (Cu–Be) 2% alloy tools was found to increase the risk of sensitization compared to background ...
ADEQUACY OF THE DATABASE
Information on the adverse health effects of beryllium has been presented for occupational exposures primarily of chronic duration and discussed in detail in Chapter 2 and summarized in Table 2-5.In short, results from occupational epidemiological studies indicate exposure can result in respiratory diseases (beryllium sensitization and CBD); …
